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Prof. Wolfram Döhner - national PI for Germany for the SECURE trial

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SECURE, or "Secondary prEvention of CardiovascUlar disease in the Elderly trial" is a European collaborative project funded by the EU Framework Programme for Research and Innovation, Horizon 2020. The five-year project involves subjects from seven different countries: Spain, Italy, Germany, France, Poland, Hungary and the Czech Republic.
Despite the established efficacy of cardiovascular medications, suboptimal adherence reduces their effectiveness and is the primary reason for suboptimal clinical benefit, contributing significantly to worsening of diseases and deaths at the population level. SECURE will be the first trial testing the efficacy of a fixed dose combination (FDC) polypill for secondary cardiovascular prevention in the elderly population (≥ 65 years old). The main objective is to evaluate the potential benefit of the FDC as a component of a cost-effective, globally available and comprehensive treatment strategy for secondary prevention of cardiovascular events (death from cardiovascular causes, nonfatal myocardial infarction, stroke, and hospitalisation requiring revascularisation) as compared to standard therapy (the three components of the polypill given separately).


Antje Meyer
Project Coordinator & Research Fellow
Centrum für Schlaganfallforschung Berlin – CSB
Charité – Universitätsmedizin Berlin
Campus Virchow-Klinikum
Augustenburger Platz 1
D - 13353 Berlin

t: +49 30 450 560 627, +49 30 450 660 627

E-Mail: secure-studie

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